A sample of colon tissue is obtained during a colonoscopy procedure using special instruments. The specimen is sent to the laboratory and fixed with special stains. The specimen is examined under the microscope for abnormal findings, such as cancer or inflammation..
Reviewed By: Subodh K. Lal, MD, gastroenterologist at Gastrointestinal Specialists of Georgia, Austell, GA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.