Medical Services Patients & Visitors Health Information For Medical Professionals Quality About Us
Text Size:  -   +  |  Print Page  |  Email Page

Hereditary amyloidosis

Definition

Hereditary amyloidosis is a condition in which abnormal protein deposits (called amyloid) form in almost every tissue in the body. Deposits most often form in the heart, kidneys, and nervous system. These protein deposits damage the tissues and interfere with how organs work.

Alternative Names

Amyloidosis - hereditary; Familial amyloidosis

Causes

Hereditary amyloidosis is passed down from parents to their children (inherited). Genes may also play a role in primary amyloidosis.

Other types of amyloidosis are not inherited. They include:

  • Senile systemic: seen in people older than 70
  • Spontaneous: occurs without a known cause
  • Secondary: results from diseases such as cancer of the blood cells (myeloma)

Specific conditions include:

Treatment

A liver transplant may be helpful. Talk to your health care provider about treatments.

References

Ferri FF. Amyloidosis. In: Ferri FF, ed. Ferri's Clinical Advisor 2016. Philadelphia, PA: Elsevier Mosby; 2016:e2-105.e5.

Gertz MA. Amyloidosis. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 188.

Seldin DC, Skinner M. Amyloidosis. In: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, eds. Kelley's Textbook of Rheumatology. 9th ed. Philadelphia, PA: Elsevier Saunders; 2013:chap 116.


Review Date: 10/27/2015
Reviewed By: Chad Haldeman-Englert, MD, FACMG, Fullerton Genetics Center, Asheville, NC. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
adam.com