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Minocycline, regular release (By mouth)

Minocycline (min-oh-SYE-kleen)

Treats infections. This medicine is a tetracycline antibiotic.

Brand Name(s):

Minocin, Minocin Kit

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to minocycline or any tetracycline antibiotic (such as doxycycline, tetracycline). Do not give this medicine to children who are less than 8 years old because it can permanently change tooth color. You should not use this medicine if you are pregnant or planning to get pregnant, or if you are breastfeeding.

How to Use This Medicine:

Capsule, Liquid, Tablet

  • Take your medicine as directed.
  • Swallow the medicine with a full glass of water. You may take the medicine with food if it upsets your stomach. Taking this medicine with food may lower your chances of getting irritation or ulcers in your esophagus (heartburn).
  • Shake the oral liquid well just before each use. Measure the medicine with a marked measuring spoon or medicine cup.
  • Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.
  • This medicine is not for long-term use.

If a dose is missed:

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine:

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not freeze the oral liquid.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are using a penicillin antibiotic (such as amoxicillin, amoxicillin/clavulanate, Amoxil®, Augmentin®, Trimox®, Veetids®), isotretinoin (Accutane®, Amnesteem®), a blood thinner such as warfarin (Coumadin®), antacids (such as Maalox®, Mylanta®), or any medicine containing aluminum, calcium, iron, or magnesium (such as multivitamins or mineral supplements).
  • Birth control pills may not work as well while you are using minocycline. To keep from getting pregnant, use an additional form of birth control with your pills. Other forms include condoms, diaphragms, or a contraceptive foam or jelly.

Warnings While Using This Medicine:

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
  • If you plan to have children, talk with your doctor before using this medicine. This medicine may affect the process of sperm cell formation in males.
  • Make sure your doctor knows if you have kidney disease, vision problems such as blurred vision, asthma, or if you are allergic to sulfites.
  • This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.
  • This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
  • This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, or red skin rash.
  • Change in how much or how often you urinate.
  • Dark-colored urine or pale stools.
  • Fever.
  • Headache or blurred vision.
  • Lightheadedness or dizziness.
  • Nausea, vomiting, diarrhea, stomach cramps, or sudden and severe stomach pain.
  • Red or black stools.
  • Swollen tongue or trouble swallowing.
  • Unusual bleeding, bruising, or weakness.
  • Yellowing of your skin or the whites of your eyes.

If you notice these less serious side effects, talk with your doctor:

  • Change in skin, nail, tooth, or gum color.
  • Dry mouth.
  • Joint pain or muscle pain.
  • Mild skin rash or itchiness.
  • Mood changes.
  • Tiredness or sleepiness.
  • Trouble hearing or ringing in your ears.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 11/4/2014


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