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Methazolamide (By mouth)

Methazolamide (meth-a-ZOLE-a-mide)

Treats glaucoma. Belongs to a class of drugs called carbonic anhydrase inhibitors.

Brand Name(s):

Neptazane

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to methazolamide or related medicine such as acetazolamide (Diamox®) or dichlorphenamide (Daranide®).

How to Use This Medicine:

Tablet

  • Use this medicine exactly as your doctor ordered.
  • May be taken with or without food or milk.
  • You will need to go to the bathroom more often while you are using this medicine. To keep from having to go too often during the night, take this medicine in the morning. If you use more than 1 dose a day, take your last dose before 6 p.m. (unless your doctor tells you differently).

If a dose is missed:

  • Use the missed dose as soon as you remember.
  • If it is almost time for your next dose, wait until then to use your medicine and skip the missed dose.
  • You should not use two doses at the same time.

How to Store and Dispose of This Medicine:

  • Store at room temperature, away from heat, moisture, and direct light.
  • Keep all medicine out of the reach of children.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are using aspirin, amphetamines (Dexedrine®), quinidine, or methenamine (Mandelamine®).

Warnings While Using This Medicine:

  • Check with your doctor before using this medicine if you have lung, kidney, or liver disease, diabetes, gout, or a poorly working adrenal gland (Addison's disease).
  • Talk with your doctor before use if you are pregnant or breastfeeding.
  • Methazolamide can make you dizzy or drowsy. Be careful if you drive a car or operate machinery.
  • You may need to eat or drink foods containing potassium, such as citrus juices, oranges, or bananas, to prevent potassium loss while using this medicine. Check with your doctor.
  • This medicine may increase the level of sugar in your blood, which can worsen sugar diabetes.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Irregular heartbeat
  • Trouble breathing
  • Skin rash, hives, or itching
  • Painful urination
  • Bloody stools or urine
  • Yellowing of skin or eyes
  • Severe nausea or vomiting
  • Unusual bleeding or bruising
  • Pain in joints or lower back

If you notice these less serious side effects, talk with your doctor:

  • Nausea, vomiting, or diarrhea
  • Dizziness, drowsiness, or lightheadedness
  • Frequent urination
  • Appetite loss or a metallic taste in mouth
  • Numbness or tingling in hands, feet, or mouth
  • Vision changes

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 12/4/2014


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