Medical Services Patients & Visitors Health Information For Medical Professionals Quality About Us
Text Size:  -   +  |  Print Page  |  Email Page

Spironolactone (By mouth)

Spironolactone (spir-on-oh-LAK-tone)

Treats several conditions, including high blood pressure. A lower blood pressure can reduce the risk of stroke and heart attack. Also treats fluid retention (edema) and related conditions such as heart failure. Used to diagnose and treat high levels of aldosterone in the body, and treats low potassium levels. This medicine is a potassium-sparing diuretic (water pill).

Brand Name(s):

Aldactone

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

Do not use this medicine if you have had an allergic reaction to spironolactone, or if you have Addison disease (an adrenal gland problem), severe kidney disease, or too much potassium in the blood. Do not use this medicine if you are not able to urinate. Do not use this medicine together with eplerenone (Inspra®).

How to Use This Medicine:

Tablet

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
  • Carefully follow your doctor's instructions about any special diet.Drink plenty of fluids if you exercise, sweat more than usual, or have diarrhea or vomiting.

If a dose is missed:

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine:

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using another diuretic (such as triamterene, Dyrenium®) or another medicine that contains spironolactone, such as Aldactazide®.
  • Ask your doctor before you use any medicine, supplement, or salt substitute that contains potassium. You could have high levels of potassium in your blood that would cause serious health problems.
  • Make sure your doctor knows if you also use cholestyramine (Questran®), digoxin (Lanoxin®), a blood thinner (such as heparin, dalteparin, enoxaparin, Fragmin®, Lovenox®), lithium (Eskalith®, Lithobid®), an NSAID pain or arthritis medicine (such as aspirin, diclofenac, indomethacin, naproxen, Advil®, Aleve®, Indocin®, Celebrex®, Voltaren®), a steroid medicine (such as hydrocortisone, methylprednisolone, prednisolone, prednisone), or blood pressure medicine (such as benazepril, enalapril, lisinopril, Avalide®, Avapro®, Benicar®, Cozaar®, Diovan®, Lotrel®, Micardis®, Vasotec®, Zestoretic®, Zestril®).
  • Alcohol, narcotic pain relievers, or sleeping pills may cause you to feel more lightheaded, dizzy, or faint when used with this medicine.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, diabetes, or a mineral imbalance (such as low magnesium or sodium in the blood).
  • This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous until you know how this medicine affects you.
  • Do not stop using the medicine without asking your doctor, even if you feel well. This medicine will not cure your high blood pressure, but it will help keep it in the normal range. You may have to take blood pressure medicine for the rest of your life.
  • Make sure any doctor or dentist who treats you knows that you are using this medicine.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, or red skin rash
  • Confusion, weakness, uneven heartbeat, trouble breathing, numbness or tingling in your hands, feet, or lips
  • Dry mouth, increased thirst, muscle cramps, nausea, or vomiting
  • Lightheadedness, dizziness, drowsiness, or fainting
  • Muscle twitching
  • Unusual bleeding, bruising, or weakness

If you notice these less serious side effects, talk with your doctor:

  • Breast swelling, enlargement, pain, or tenderness

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 7/4/2014


The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites.
Copyright © 1984- Truven Health Analytics. All rights reserved.

Thomson & A.D.A.M
A.D.A.M. content is best viewed in IE9 or above, Fire Fox and chrome browser.