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Enalapril (By mouth)

Enalapril (en-AL-a-pril)

This is an ACE inhibitor that treats high blood pressure, congestive heart failure, and other heart problems. A lower blood pressure can reduce the risk of stroke and heart attack.

Brand Name(s):

Epaned, Vasotec

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use if you had an allergic reaction to enalapril, or if you are pregnant.

How to Use This Medicine:

Liquid, Tablet

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
  • Oral liquid:Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.
  • If your child cannot swallow the tablets, an oral liquid may be given. Ask your doctor or pharmacist about this.
  • Missed dose:Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Epaned? oral liquid: Store at room temperature for up to 60 days. Vasotec® mixed oral liquid: Keep in the refrigerator and store it for up to 30 days. Do not freeze.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Do not use this medicine together with aliskiren if you have diabetes.
  • Some foods and medicines can affect how enalapril works. Tell your doctor if you are using any of the following:
    • Aliskiren
    • Lithium
    • Diuretic (water pill)
    • NSAID pain or arthritis medicine (such as aspirin, diclofenac, ibuprofen, naproxen, celecoxib)
    • Supplement or salt substitute that contains potassium

Warnings While Using This Medicine:

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
  • Tell your doctor if you are breastfeeding, or if you have kidney problems, liver disease, diabetes, heart or blood vessel disease, a mineral imbalance (such as low sodium levels in the blood), an autoimmune disorder, angioedema, or a history of angioedema after receiving an ACE inhibitor.
  • This medicine may cause the following problems:
    • Intestinal swelling
    • Liver problems
    • Kidney problems
  • This medicine could lower your blood pressure too much, especially when you first use it or if you are dehydrated.
  • This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Change in how much or how often you urinate, problems urinating
  • Confusion, weakness, uneven heartbeat, trouble breathing, numbness in your hands, feet, or lips
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
  • Lightheadedness, dizziness, or fainting
  • Severe stomach pain (with or without nausea or vomiting)

If you notice these less serious side effects, talk with your doctor:

  • Dry cough

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 9/4/2014


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