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Lisinopril (By mouth)

Lisinopril (lye-SIN-oh-pril)

This medicine is an ACE inhibitor that treats high blood pressure and heart failure.

Brand Name(s):

Lytensopril, Lytensopril-90, Prinivil, Zestril

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use this medicine if you had an allergic reaction to lisinopril, or if you are pregnant, or have a history of angioedema.

How to Use This Medicine:

Tablet

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
  • Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.
  • Oral liquid will be given if your child cannot swallow the tablets. Shake well just before each use.
  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. The liquid can be stored at or below room temperature for up to 4 weeks.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Do not use this medicine together with aliskiren if you have diabetes.
  • Ask your doctor before you use medicines, supplements, or salt substitutes that contain potassium.
  • Some medicines may affect how lisinopril works. Tell your doctor if you are using any of the following:
    • Diuretics (such as amiloride, eplerenone, spironolactone, triamterene)
    • Gold injections
    • Insulin or oral antidiabetics
    • Lithium
    • NSAID pain or arthritis medicine (such as aspirin, diclofenac, ibuprofen, naproxen, celecoxib)

Warnings While Using This Medicine:

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
  • Tell your doctor if you are breastfeeding, or if you have kidney or heart problems, congestive heart failure, liver disease, low blood pressure, or a mineral imbalance (such as high potassium or low sodium in the blood). Tell your doctor if you have diabetes or an autoimmune disorder (such as a collagen vascular disease).
  • This medicine may cause the following problems:
    • Intestinal swelling
    • Liver problems
  • This medicine could lower your blood pressure too much, especially when you first use it or if you are dehydrated.
  • This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Change in how much or how often you urinate
  • Confusion, weakness, uneven heartbeat, shortness of breath, numbness or tingling in your hands, feet, or lips
  • Dark-colored urine or pale stools, nausea, vomiting, loss of appetite, pain in your upper stomach, yellow skin or eyes
  • Fever, chills, sore throat, or body aches
  • Lightheadedness, dizziness, or fainting
  • Severe stomach pain (with or without nausea or vomiting)

If you notice these less serious side effects, talk with your doctor:

  • Dry cough
  • Headache

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 8/4/2014


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