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Piroxicam (By mouth)

Piroxicam (pir-OX-i-kam)

Treats pain. This is an NSAID.

Brand Name(s):

Feldene, Therafeldamine

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use it if you had an allergic reaction to piroxicam, aspirin, or another NSAID medicine.

How to Use This Medicine:

Capsule, Tablet

  • Your doctor will tell you how much medicine to use. Do not use more than directed.
  • It is best to take this medicine with food or milk.
  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some foods and medicines can affect how piroxicam works. Tell your doctor if you are using any of the following:
    • Lithium, methotrexate
    • Another NSAID medicine (including aspirin, celecoxib, ibuprofen, naproxen)
    • Blood thinner (including warfarin)
    • ACE inhibitor
    • Diuretic (water pill)
    • Steroid medicine (including dexamethasone, hydrocortisone, methylprednisolone, prednisolone, prednisone)

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant. It is not safe to use this medicine during the third trimester of pregnancy.
  • Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, asthma, bleeding problems, heart failure, high blood pressure, other heart or circulation problems, or stomach ulcers or bleeding.
  • This medicine may cause the following problems:
    • Increased risk of blot clots, heart attack, or stroke
    • Bleeding in your stomach or intestines
    • Kidney problems
    • Liver problems
  • Ovulation may be delayed in some women while this medicine is being used. Talk to your doctor if you have concerns about this.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, or red skin rash
  • Bloody or black, tarry stools, severe stomach pain, vomiting blood or something that looks like coffee grounds
  • Chest pain that may spread, trouble breathing, nausea, unusual sweating, fainting
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
  • Decrease in how much or how often you urinate
  • Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking
  • Rapid weight gain, swelling in your hands, ankles, or feet
  • Unusual bleeding, bruising, or weakness

If you notice these less serious side effects, talk with your doctor:

  • Dizziness
  • Mild nausea, vomiting, gas, or constipation

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 11/18/2015

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