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Nizatidine (By mouth)

Nizatidine (nye-ZA-ti-deen)

Treats ulcers, gastroesophageal reflux disease (GERD), and conditions that cause the stomach to produce too much stomach acid. Belongs to a class of drugs called histamine H2-blockers.

Brand Name(s):

Axid, Axid AR, Axid Pulvules

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have ever had an allergic reaction to famotidine or to similar medicines such as ranitidine (Zantac®), cimetidine (Tagamet®), or famotidine (Pepcid®, Fluxid?).

How to Use This Medicine:

Tablet, Liquid, Capsule

  • Take your medicine as directed.
  • Follow the instructions on the medicine label if you are using this medicine without a prescription.
  • If you are taking: One dose a day, take at bedtime. Two doses a day, take one in the morning and one at bedtime. Several doses daily, take doses with your meals and at bedtime.
  • Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

If a dose is missed:

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine:

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • You should not use nizatidine within 2 hours before or after taking ketoconazole (an antifungal drug).
  • Avoid using large amounts of aspirin while taking nizatidine.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breast feeding, or if you have kidney disease or liver disease.
  • Nizatidine may not work as well if you smoke.
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Dark-colored urine or pale stools.
  • Unusual bleeding, bruising, or weakness.
  • Yellowing of your skin or the whites of your eyes.

If you notice these less serious side effects, talk with your doctor:

  • Breast tenderness (or breast swelling in men).
  • Dizziness.
  • Mild nausea.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 11/4/2014


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