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Sulfanilamide (Vaginal)

Sulfanilamide (sul-FAN-i-la-mide)

Treats vaginal yeast and bacterial infections. Belongs to a class of drugs known as sulfonamides or sulfa drugs.

Brand Name(s):

AVC, Avc

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to any sulfonamide or sulfa drug (such as Gantanol® or Gantrisin®). Let your doctor know if you have a history of kidney or blood disorders or porphyria (a metabolic disorder).

How to Use This Medicine:

Cream, Suppository

  • Your doctor will tell you how much medicine to take and how often. Wash your hands before and after using this medicine.
  • The medicine is a cream that is in a tube. You will use an applicator to put the cream into your vagina. The applicator is an empty plastic tube called a barrel that is open at one end and has a plunger at the other end.
  • Remove the cap from the end of the tube of cream. Squeeze the cream from the tube into the open end of the applicator until the barrel is filled with cream.
  • If you are using the vaginal suppository, unwrap the suppository and place it in the applicator with the pointed side up. You may wet the suppository with warm water or a water soluble lubricating gel (K-Y® Jelly). You should not use petroleum jelly (Vaseline®).
  • Put the applicator into your vagina as far as you can and push the plunger all the way in. Remove the applicator and wash it with warm, soapy water.
  • Wear only clean cotton underwear (panties) instead of nylon or rayon underwear. The medicine will come out of your vagina, so wear a minipad or sanitary napkin to protect your clothing. Be sure to use this medicine for the full course of your prescription. Continue to use it even if your menstrual period begins. Use pads rather than tampons.

If a dose is missed:

  • Insert the missed dose as soon as possible.
  • Skip the missed dose if it is almost time for your next regular dose.
  • You should not use two doses at the same time.

How to Store and Dispose of This Medicine:

  • Store at room temperature in a closed container, away from heat, moisture, and direct light. Do not freeze.
  • Keep all medicine out of the reach of children.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Do not douche or use any other vaginal products while using this medicine unless your doctor tells you to.

Warnings While Using This Medicine:

  • If you are pregnant or breastfeeding, talk to your doctor before using this medicine.
  • Keep this cream away from your mouth and eyes (wash your hands after handling this medicine).

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Severe vaginal itching or burning
  • Skin rash or hives and itching

If you notice these less serious side effects, talk with your doctor:

  • Mild vaginal irritation or burning

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 7/4/2014


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