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Ciprofloxacin (Injection)

Ciprofloxacin (sip-roe-FLOX-a-sin)

Treats infections and is given to people who have been exposed to anthrax. This medicine is a quinolone antibiotic.

Brand Name(s):

Amerinet Choice Ciprofloxacin, Cipro IV, NovaPlus Ciprofloxacin

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not receive this medicine if you had an allergic reaction to ciprofloxacin or similar medicines.

How to Use This Medicine:

Injectable

  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
  • A nurse or other health provider will give you this medicine.
  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
  • Your doctor may give you a few doses of this medicine until your condition improves. Then you may be switched to an oral medicine that works the same way. Talk to your doctor if you have concerns about this.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Do not use this medicine together with tizanidine.
  • Some medicines and foods can affect how ciprofloxacin works. Tell your doctor if you are taking any of the following:
    • Clozapine, olanzapine, cyclosporine, lidocaine, methotrexate, phenytoin, probenecid, ropinirole, theophylline
    • Blood thinner, such as warfarin
    • Depression medicine
    • Diabetes medicine
    • Heart medicine
    • Medicine to treat mental illness
    • NSAID pain or arthritis medicine, such as aspirin, diclofenac, ibuprofen, naproxen, celecoxib
    • Steroid medicine, such as hydrocortisone, methylprednisolone, prednisone
  • Take sucralfate, didanosine, antacids, or multivitamins 2 hours before or 6 hours after you take this medicine.
  • This medicine slows the digestion of caffeine, so it might affect you for longer than normal.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney, liver, or heart disease, diabetes, myasthenia gravis, or a history of heart rhythm problems, seizures, or stroke. Tell your doctor if you have ever had tendon or joint problems, including rheumatoid arthritis, or if you have received a transplant.
  • This medicine may cause the following problems:
    • Tendinitis and tendon rupture (may happen after treatment ends)
    • Liver damage
    • Severe diarrhea
    • Nerve damage in the arms or legs
    • Heart rhythm changes
  • This medicine may make you dizzy, drowsy, or lightheaded. Do not drive or do anything that could be dangerous until you know how this medicine affects you.
  • Drink extra fluids so you will urinate more often and help prevent kidney problems.
  • This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.
  • This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, red skin rash
  • Change in how much or how often you urinate
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
  • Diarrhea that may contain blood
  • Fainting, dizziness, or lightheadedness
  • Fast, slow, or uneven heartbeat
  • Numbness, tingling, weakness, or burning pain in your hands, arms, legs, or feet
  • Pain, stiffness, swelling, or bruises around your ankle, leg, shoulder, or other joint
  • Seizures, severe headache, unusual thoughts or behavior, trouble sleeping, confusion
  • Unusual bleeding, bruising, or weakness

If you notice these less serious side effects, talk with your doctor:

  • Pain, swelling, or redness where the needle is placed

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 12/4/2014


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