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Fosfomycin (By mouth)

Fosfomycin Tromethamine (fos-foe-MYE-sin troe-METH-a-meen)

Treats urinary tract infections (UTI). This medicine is an antibiotic.

Brand Name(s):

Monurol

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to fosfomycin.

How to Use This Medicine:

Powder

  • Take your medicine as directed.
  • Only one dose of this medicine is needed to treat your UTI. The medicine stays in your body to fight the infection.
  • You may take this medicine with or without food.
  • The medicine is an orange-flavored powder that must be mixed with water before using. Never swallow the medicine in its dry form.
  • To use:
    • Open the packet and pour all of the powder into 3 to 4 ounces (1/2 cup) of water. Do not use hot water.
    • Stir until the powder is dissolved, and drink the mixture right away.
  • Drink extra fluids so you will pass more urine while you are using this medicine. This will keep your bladder working well and help prevent bladder problems.

If a dose is missed:

  • You should only use one dose of the medicine to treat your UTI.

How to Store and Dispose of This Medicine:

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are using any medicine that causes food to move more quickly through your stomach, such as metoclopramide (Reglan®).

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease or diarrhea.
  • This medicine may cause diarrhea, and in some cases it can be severe. It may occur 2 months or more after you stop taking this medicine. Do not take any medicine to treat diarrhea without first checking with your doctor. If you have any questions or if mild diarrhea continues or gets worse, check with your doctor.
  • Call your doctor if your symptoms do not improve or if they get worse.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Severe and watery diarrhea that may contain blood.
  • Severe stomach pain.
  • Vision changes.
  • Yellowing of your skin or the whites of your eyes.

If you notice these less serious side effects, talk with your doctor:

  • Headache or dizziness.
  • Mild diarrhea, nausea, heartburn, indigestion, or upset stomach.
  • Vaginal itching or discharge.
  • Weakness.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 8/4/2014


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