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Bicalutamide (By mouth)

Bicalutamide (bye-ka-LOO-ta-mide)

Treats prostate cancer. This medicine is an antiandrogen.

Brand Name(s):

Casodex

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use it if you had an allergic reaction to bicalutamide or if you are a woman.

How to Use This Medicine:

Tablet

  • Take your medicine as directed.
  • You may take this medicine with or without food.
  • Take this medicine at the same time each day.
  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines may affect how bicalutamide works. Tell your doctor if you are taking any of the following:
    • A blood thinner such as warfarin
    • Midazolam

Warnings While Using This Medicine:

  • Tell your doctor if you have liver disease or diabetes.
  • This medicine may cause the following problems:
    • Liver problems
    • Breast swelling and pain
    • Infertility
  • This medicine may affect the results of a prostate specific antigen (PSA) test. Tell all doctors who treat you that you are taking this medicine.
  • This medicine may make you drowsy or sleepy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Change in how much or how often you urinate, difficult or painful urination
  • Chest pain
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
  • Fast, slow, pounding, or uneven heartbeat
  • Fever, chills, cough, sore throat, sweating, and body aches
  • Increased hunger or thirst
  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet
  • Shortness of breath or trouble breathing
  • Swelling in your hands, ankles, or feet
  • Unusual bleeding, bruising, or weakness

If you notice these less serious side effects, talk with your doctor:

  • Back or bone pain, dizziness, or headache
  • Breast pain, swelling, or tenderness
  • Trouble having sex, or loss of interest in sex
  • Trouble sleeping, or unusual tiredness
  • Warmth or redness in your face, neck, arms, or upper chest

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 8/4/2014


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