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Glycopyrrolate (By mouth)

Glycopyrrolate (glye-koe-PIR-oh-late)

Treats peptic ulcers. Also used to treat severe drooling caused by certain conditions (such as cerebral palsy) in children 3 to 16 years of age.

Brand Name(s):

Cuvposa, Glycate, Robinul, Robinul Forte

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to glycopyrrolate, or if you have glaucoma, myasthenia gravis, or trouble urinating because of an enlarged prostate or other blockage. You should not use this medicine if you have certain problems with digestion, including severe colitis or something physically blocking digestion. Do not take this medicine if you or your child is receiving potassium chloride tablets or other potassium supplements (in capsule or tablet forms).

How to Use This Medicine:

Liquid, Tablet

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
  • Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.
  • You or your child should take the oral liquid at least one hour before or two hours after meals.
  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

If a dose is missed:

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine:

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you or your child is receiving amantadine (Symmetrel®), atenolol (Tenormin®), digoxin (Lanoxin®), haloperidol (Haldol®), metformin (Glucophage®), or levodopa (Sinemet®).

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you or your child has kidney disease, liver disease, heart disease, congestive heart failure, heart rhythm problems, high blood pressure, nerve problems, an enlarged prostate, or an overactive thyroid. Tell your doctor if you or your child has hiatal hernia, heartburn, diarrhea, colitis, a colostomy or ileostomy, or any other problems with your stomach, bowel, or digestive system.
  • This medicine may cause constipation or diarrhea. Constipation or diarrhea can be an early symptom of a serious bowel problem. Stop using this medicine and check with your doctor right away if you or your child has constipation, diarrhea, abdominal or stomach distention (swelling), pain, nausea, or vomiting.
  • Stop using this medicine and check with your doctor right away if your child is unable to urinate, has dry diapers or undergarments, or has the following symptoms while using this medicine: crying, irritability, decrease in the frequency of urine, or difficult or painful urination.
  • If you or your child develops a skin rash, hives, or any allergic reaction to this medicine, stop taking the medicine and check with your doctor as soon as possible.
  • Be careful during hot weather or exercising. This medicine may make you or your child sweat less, so you could get overheated more easily.
  • This medicine may make you drowsy or cause blurred vision. Avoid driving, using machines, or doing anything else that could be dangerous if you or your child is not alert.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Abdominal pain or swelling.
  • Decrease in how much or how often you urinate, painful urination.
  • Diarrhea or constipation.
  • Fast or pounding heartbeat.
  • Fever, chills, cough, sore throat, stuffy or runny nose, and body aches.
  • Lightheadedness or fainting.
  • Muscle weakness or stiffness.
  • Trouble with breathing.
  • Warmth or redness in your face, neck, arms, or upper chest.

If you notice these less serious side effects, talk with your doctor:

  • Confusion, nervousness.
  • Dry mouth.
  • Flushing.
  • Light bothering your eyes.
  • Nasal congestion.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 8/4/2014


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