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Hydrocortisone (Rectal)

Hydrocortisone (hye-droe-KOR-ti-sone)

Treats inflammation, itching, and discomfort of the rectum including inflamed hemorrhoids. Belongs to a class of drugs called corticosteroids.

Brand Name(s):

Anu-Med Hc, Anucort HC, Anucort-HC, Anusol-HC, Anusol-Hc, Cortifoam, GRx HiCort 25, Hemril-30, Procto-Kit 1%, Procto-Kit 2.5%, Procto-Pak, Proctocort, Proctosol-HC, Proctozone-Hc, Rectacort-HC

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to hydrocortisone or recent colostomy surgery.

How to Use This Medicine:

Cream, Suppository, Foam

  • Your doctor will tell you how much to take and how often.
  • Read and follow the instructions that came with this medicine.
  • Wash your hands before and after using.
  • The cream medicine may be used outside the rectal area. Put a thin layer on the affected area. Rub in gently.
  • The cream may also be used inside the rectum by using the plastic applicator that comes in the box. Screw the applicator to the tube of medicine. Gently insert the applicator into the rectum. Squeeze the tube of medicine. After applying the correct amount of medicine, remove the applicator from the rectum.
  • Insert the foam into your rectum using the applicator that comes with your medicine. Do not put any part of the foam container into your rectum. Follow the directions that came with your medicine.
  • Wash the cream or foam applicator and put it back in the box.
  • Remove the wrapper from the suppository if one is present.
  • Moisten the suppository with water.
  • To use the suppository, lie on your side with your lower leg straightened out and your upper leg bent up towards your stomach.
  • Spread your buttocks and insert the suppository into the rectum about 1 inch with your finger. Hold your buttocks together for about 1 minute.
  • Remain lying down for at least 15 minutes to keep the suppository from coming out.
  • If you have any questions about this medicine, ask your doctor or pharmacist.

If a dose is missed:

  • Use the missed dose as soon as possible.
  • Skip the missed dose if it is almost time for your next regular dose.
  • You should not use two doses at the same time.

How to Store and Dispose of This Medicine:

  • Store at room temperature, away from heat, moisture, and direct light. Do not freeze.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • You should not use other rectal medicines while using this medicine without first checking with your doctor.

Warnings While Using This Medicine:

  • Talk with your doctor before using if you are pregnant or have an infection such as herpes.
  • You should not use more often or for a longer time than your doctor ordered.
  • You should not use this medicine for other rectal conditions without first checking with your doctor.
  • The suppository may cause staining of your clothes. Use a minipad to avoid staining your clothes.

Possible Side Effects While Using This Medicine:

If you notice these less serious side effects, talk with your doctor:

  • Rectal irritation, burning, or itching

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 10/4/2014


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