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Adalimumab (Injection)

Adalimumab (a-da-LIM-ue-mab)

Treats arthritis, plaque psoriasis, ankylosing spondylitis, Crohn disease, and ulcerative colitis.

Brand Name(s):

Humira

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use it if you had an allergic reaction to adalimumab.

How to Use This Medicine:

Injectable

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin.
  • A nurse or other health provider will give you this medicine.
  • You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.
  • Use a new needle and syringe each time you inject your medicine.
  • Do not use the syringe or pen if the liquid is cloudy, discolored, or has particles floating in it.
  • You will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas.
  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
  • If you store this medicine at home, keep it in the refrigerator. Do not freeze. Protect the medicine from light. Keep your medicine and supplies in the original packages until you are ready to use them. If you are traveling, store the medicine in a cooler with an ice pack.
  • Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Do not take this medicine together with abatacept, anakinra, certolizumab pegol, etanercept, golimumab, or infliximab.
  • Some medicines can affect how adalimumab works. Tell your doctor if you are taking any of the following:
    • A blood thinner, such as warfarin
    • Azathioprine
    • Cyclosporine
    • Medicine that weakens the immune system, such as a steroid or cancer medicine
    • Mercaptopurine
    • Rituximab
    • Theophylline
  • This medicine may interfere with vaccines. Ask your doctor before you get a flu shot or any other vaccines. Your child's vaccines need to be current before he or she begins using adalimumab.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, a history of cancer, COPD, congestive heart failure, diabetes, psoriasis, any type of infection (such as hepatitis B or tuberculosis), or an infection that keeps coming back. Tell your doctor if you have multiple sclerosis, optic neuritis, problems with your immune system, or a history of Guillain-Barré syndrome.
  • Tell your doctor if you are scheduled for surgery.
  • Tell your doctor if you have a latex allergy. The needle cover of the syringe may cause allergic reactions in people who are sensitive to latex.
  • You will need to have a skin test for tuberculosis (TB) before you start this medicine. Tell your doctor if you or anyone in your home has ever had a positive TB skin test or been exposed to TB.
  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
  • This medicine may cause the following problems:
    • A lupus-like syndrome
    • Certain types of cancer
    • Increased risk for infection
    • New or worsening congestive heart failure
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, red skin rash, or red, scaly patches on the skin
  • Changes in vision
  • Chest pain or uneven heartbeat, or trouble breathing
  • Cough, fever, chills, runny or stuffy nose, sore throat, and body aches
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, pain in your upper stomach, yellow skin or eyes
  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet, or joint pain
  • Pain with urination, or a change in how much or how often you urinate
  • Rapid weight gain, swelling in your hands, ankles, lower legs, or feet
  • Sores or white patches on your lips, mouth, or throat
  • Swollen glands in your neck, underarms, or groin
  • Unusual bleeding, bruising, tiredness, weakness, or weight loss

If you notice these less serious side effects, talk with your doctor:

  • Headache
  • Mild skin rash
  • Redness, itching, bruising, bleeding, pain, or swelling where the shot was given

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 11/4/2014


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