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Fosamprenavir (By mouth)

Fosamprenavir (fos-am-PREN-a-vir)

Treats HIV infection. This medicine does not cure HIV or AIDS, but combinations of drugs may slow the progress of the disease.

Brand Name(s):


There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use it if you had an allergic reaction to fosamprenavir or amprenavir.

How to Use This Medicine:

Liquid, Tablet

  • Your doctor will tell you how much medicine to use. Do not use more than directed.
  • Tablets: Take with or without food.
  • Oral liquid: Children should take the oral liquid with food. Adults should take it without food. Retake if you vomit within 30 minutes of taking the medicine. Shake the oral liquid well just before each use. Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.
  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
  • Fosamprenavir is used together with other medicines to treat HIV infection. Take all of the medicines your doctor has prescribed at the right time of day and in the correct order. Do not stop using your medicine unless your doctor tells you to.
  • Do not stop using this medicine without checking first with your doctor. If you stop the medicine even briefly, the virus may become harder to treat. Contact your doctor or pharmacist when your supply is running low so you do not run out.
  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Oral liquid: Store in the refrigerator or at room temperature. Do not freeze.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Do not use this medicine if you are also using alfuzosin, cisapride, delavirdine, lovastatin, midazolam, pimozide, rifampin, sildenafil, simvastatin, triazolam, St John's wort, or an ergot medicine (including dihydroergotamine, ergonovine, ergotamine, methylergonovine). Do not use flecainide or propafenone if you are also using ritonavir together with this medicine.
  • Many other drugs can interact with fosamprenavir. Make sure your doctor knows about all other medicines and supplements you are using.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or if you have kidney disease, liver disease (especially hepatitis), diabetes, high cholesterol, or hemophilia. Tell your doctor if you are allergic to sulfa drugs.
  • Do not breastfeed. You can spread HIV or AIDS to your baby through your breast milk.
  • This medicine may cause the following problems:
    • Serious skin reactions
    • High blood sugar levels, a problem that could become permanent
    • Kidney stones
  • Your immune system may get stronger when you start taking an HIV medicine. Infections that were hidden in your body, such as pneumonia or tuberculosis, might start to have symptoms. Tell your doctor right away if you notice any changes in your health.
  • This medicine will not keep you from giving HIV to others. Always practice safe sex, even if your partner also has HIV. Do not share needles or other items that may have blood or body fluids on them.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, red skin rash
  • Blood in the urine, pain in your side, pain when you urinate
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
  • Increased hunger or thirst, increased urination, unexplained weight loss
  • Trouble breathing, tiredness, uneven heartbeat, yellow skin or eyes

If you notice these less serious side effects, talk with your doctor:

  • Diarrhea, nausea, vomiting
  • Weight gain around your neck, upper back, breast, face, or waist

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 11/18/2015

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