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Benazepril (By mouth)

Benazepril (ben-AZ-e-pril)

Treats high blood pressure. A lower blood pressure can reduce the risk of stroke and heart attack. This medicine is an angiotensin-converting enzyme (ACE) inhibitor.

Brand Name(s):

Lotensin

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

Do not use this medicine if you have had an allergic reaction to benazepril or to similar medicines such as enalapril, lisinopril, Lotrel®, Vasotec®, Zestril®, or Zesteretic®. Do not use this medicine if you are pregnant or have a history of angioedema (swelling of the hands, arms, face, lips, tongue, or throat). Do not use this medicine together with aliskiren (Tekturna®) if you have diabetes.

How to Use This Medicine:

Tablet

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
  • Carefully follow your doctor's instructions about any special diet.Be sure to drink plenty of fluids if you exercise, sweat more than usual, or have diarrhea or vomiting.
  • An oral liquid may be given if your child cannot swallow the tablets. Ask your doctor or pharmacist about this.
  • Shake the liquid well just before you measure the dose. Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

If a dose is missed:

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine:

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Mixed oral liquidshould be stored in the refrigerator for up to 30 days. Do not freeze.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Do not use this medicine together with aliskiren (Tekturna®) if you have diabetes.
  • Make sure your doctor knows if you are using adiuretic (water pill, such as amiloride, spironolactone, triamterene, Aldactone®).
  • Make sure your doctor knows if you are also using lithium (Eskalith®, Lithobid®) or gold injections (such as sodium aurothiomalate). Tell your doctor if you are also using insulin or any oral diabetes medicine (such as glimepiride, glyburide, metformin, Actos®, Janumet®, Januvia®), or NSAID pain or arthritis medicine (such as aspirin, diclofenac, ibuprofen, naproxen, Advil®, Aleve®, Celebrex®, Voltaren®).
  • Ask your doctor before you use medicines, supplements, or salt substitutes that contain potassium.

Warnings While Using This Medicine:

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
  • Make sure your doctor knows if you are breastfeeding, or if you have kidney problems, liver disease, diabetes, congestive heart failure, heart disease, dehydration, low blood pressure, or a mineral imbalance (high or low potassium or sodium in the blood). Tell your doctor if you have an autoimmune disorder (such as a collagen vascular disease, lupus, rheumatoid arthritis, or scleroderma).
  • Call your doctor right away if you have severe stomach pain (with or without nausea or vomiting). This could be a symptom of intestinal angioedema.
  • This medicine could lower your blood pressure too much and cause you to feel dizzy or lightheaded. Stand or sit up slowly if you are dizzy. This is more likely to happen when you begin to use the medicine or if you become dehydrated. Do not drive, use machines, or do anything else that could be dangerous until you know how this medicine affects you.
  • Tell your doctor if you have a fever, chills, or sore throat. These could be symptoms of an infection caused by low white blood cell counts.
  • Stop taking this medicine and tell your doctor right away if you have dark-colored urine or pale stools, nausea, vomiting, loss of appetite, pain in your upper stomach, or yellow skin or eyes. These could be symptoms of a serious liver problem.
  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.
  • Angioedema and other allergic reactions are rare, but are more common among black patients. This medicine may be less effective in black patients.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Do not stop using this medicine without asking your doctor, even if you feel well. This medicine will not cure your high blood pressure, but it will help keep it in normal range. You may have to take blood pressure medicine for the rest of your life.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, red skin rash
  • Change in how much or how often you urinate
  • Chest pain (may be related to your disease and not a side effect)
  • Confusion, body weakness, uneven heartbeat, trouble breathing, numbness or tingling in your hands, feet, or lips
  • Dark-colored urine or pale stools, nausea, vomiting, loss of appetite, or pain in your upper stomach, yellow skin or eyes
  • Fast, pounding, or uneven heartbeat
  • Fever, chills, cough, sore throat, and body aches
  • Lightheadedness, dizziness, or fainting
  • Severe stomach pain (with or without nausea or vomiting)

If you notice these less serious side effects, talk with your doctor:

  • Dry cough
  • Headache

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 4/4/2014
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