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Docusate (Rectal)

Docusate (DOK-ue-sate)

Treats constipation caused by problems with bowel movements, or not having a bowel movement often enough. This medicine is a stool softener.

Brand Name(s):

DocuSol Kids, Docusol, Enemeez Mini Enema

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to docusate, or if you have a bowel disorder such as Crohn's disease or ulcerative colitis. Do not use this medicine if you have had stomach pain, nausea, or vomiting for longer than 1 week.

How to Use This Medicine:

Enema, Suppository

  • Take your medicine as directed.
  • Follow the instructions on the medicine label if you are using this medicine without a prescription.
  • Wash your hands with soap and water before and after using this medicine. Remove the foil or wrapper from the suppository before inserting it.
  • Shake the enema bottle gently just before each use. Remove the protective cap from the bottle tip.
  • Lie on your left side with your left leg straight or slightly bent, and your right knee bent upward. Insert the applicator tip into your rectum about an inch. Gently squeeze the bottom of the bottle to release the enema.
  • Remove the bottle and throw it away.
  • You may need to hold the liquid in your rectum for several minutes or hours. This may be difficult or feel uncomfortable. It should become easier to do as you continue to use the medicine.
  • Never take rectal suppositories by mouth.
  • To make the suppository easier to insert, you may use a lubricating gel such as K-Y® Jelly, but do not use petroleum jelly (Vaseline®).
  • Lie on your left side with your left leg straight or slightly bent, and your right knee bent upward. Gently push the pointed end of the suppository into the rectum about 1 inch.
  • Keep lying down for about 15 minutes to keep the suppository from coming out before it melts. Then, wash your hands again.
  • Carefully follow your doctor's instructions about diet and exercise while you are using this medicine. Drinking plenty of water and other fluids will also help soften your stools.

How to Store and Dispose of This Medicine:

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • You may store the suppositories in the refrigerator, but do not freeze them.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Do not use this medicine together with aspirin or mineral oil unless your doctor tells you to.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breast feeding.
  • Do not use this medicine for longer than 1 week unless your doctor tells you to.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Bleeding from your rectum, bloody or black tarry stool.
  • Nausea, vomiting, or stomach pain after using the medicine.
  • No bowel movement within 3 days after using this medicine.

If you notice these less serious side effects, talk with your doctor:

  • Itching or irritation around your rectum.
  • Mild nausea or diarrhea.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 7/4/2014


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