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Tranexamic acid (Injection)

Tranexamic Acid (tran-ex-AM-ik AS-id)

Given before tooth removal to prevent or control bleeding episodes in people who have hemophilia.

Brand Name(s):

Cyklokapron, Novaplus Tranexamic Acid

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not receive this medicine if you have had an allergic reaction to tranexamic acid, or if you have an eye disorder that causes you to have problems seeing certain colors. You should not receive this medicine if you have a certain type of head injury or bleeding in your brain. You should not receive this medicine if you have an active or a history of blood clots.

How to Use This Medicine:

Injectable

  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
  • A nurse or other health provider will give you this medicine.

If a dose is missed:

  • This medicine needs to be given on a fixed schedule. Keep all appointments. If you miss a dose, call your doctor or pharmacist for instructions.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are receiving any other medicine to help blood clotting. Tell your doctor if you are using factor IX complex (such as BeneFIX®, Proplex® T) or anti-inhibitor coagulant concentrates (such as Feiba VH®).

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney problems, any other blood or circulation problems, urinary tract problems, or a history of seizures. Tell your doctor if you have a blood clotting problem called disseminated intravascular coagulation or DIC.
  • If you or your child will be receiving this medicine for longer than several days, your doctor may want you to have your eyes checked regularly by an eye doctor. This will allow your doctor to check for unwanted effects that may be caused by this medicine.
  • This medicine may make you dizzy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments. Blood tests will be needed to check for unwanted effects.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest pain, shortness of breath, or coughing up blood.
  • Dark or bloody urine, trouble urinating, or a decrease in how much or how often you urinate.
  • Lightheadedness, dizziness, or fainting.
  • Numbness or weakness in your arm or leg, or on one side of your body.
  • Pain in your lower calf.
  • Seizures.
  • Sudden or severe headache, or problems with speech or walking.
  • Vision changes.

If you notice these less serious side effects, talk with your doctor:

  • Nausea, vomiting, or diarrhea.
  • Sudden mood changes.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 12/4/2014


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