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Benzoyl peroxide/clindamycin (On the skin)

Benzoyl Peroxide (BEN-zoe-il per-OX-ide), Clindamycin (klin-da-MYE-sin)

Treats severe acne.

Brand Name(s):

Acanya, Benzaclin, Duac

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to benzoyl peroxide, clindamycin, or lincomycin. You should not use this medicine if you have bowel problems such as ulcerative colitis, severe diarrhea caused by antibiotics, or a history of regional enteritis (swelling of the bowels).

How to Use This Medicine:

Gel/Jelly

  • Take your medicine as directed.
  • Use this medicine only on your skin. Rinse it off right away if it gets on a cut or scrape. Do not get the medicine in your eyes, nose, or mouth.
  • Wash your hands with soap and water before and after you use this medicine.
  • Before applying this medicine, wash your skin gently with warm water and pat it dry.
  • Apply a thin layer of the medicine to the affected area. Rub it in gently.

If a dose is missed:

  • Apply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine:

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist or doctor how to dispose of the medicine container and any leftover or expired medicine. Throw away any unused medicine after 3 months.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Do not put cosmetics or skin care products on the treated skin.
  • Tell your doctor if you are using any other medicine for the treatment of acne.
  • Make sure your doctor knows if you are also using products containing erythromycin (Ery-tab®, E-Mycin®) or any other topical skin treatments such as skin peeling agents.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have any fungus infection on your skin.
  • Ask your doctor before you take any medicine to stop severe diarrhea.
  • Do not use this medicine to treat a skin problem your doctor has not examined.
  • This medicine can cause irritation. Do not get this medicine into your eyes, nose, or mouth.
  • If you develop severe swelling, shortness of breath, or any allergic reaction to this medicine, stop using the medicine and check with your doctor right away.
  • This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.
  • Do not apply the medicine to your hair or to any colored fabric. This medicine may cause bleaching.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Severe diarrhea or diarrhea that may contain blood.

If you notice these less serious side effects, talk with your doctor:

  • Dry skin, rash, itching, or peeling skin.
  • Irritation of your skin where the medicine is applied.
  • Sunburn.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 4/4/2014
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