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Chloroprocaine (Injection)

Chloroprocaine (klor-oh-PROE-kane)

This medicine is used before a surgery to numb your skin or some parts of your body. This medicine is a local anesthetic.

Brand Name(s):

Nesacaine, Nesacaine-MPF

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not receive this medicine if you have had an allergic reaction to chloroprocaine or any of the PABA ester group of drugs.

How to Use This Medicine:

Injectable

  • This medicine will be injected through a needle into your back (spinal cord) before a surgery.
  • A nurse or other health provider will give you this medicine.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are using ergot medicines such as Cafergot®, Ergomar®, or Wigraine®, or sulfonamides such as Bactrim®, Cotrim®, or Septra®.
  • Make sure your doctor knows if you are using medicines to treat depression such as amitriptyline, doxepin, nortriptyline , Elavil®, Pamelor®, or Sinequan®, or phenothiazines such as prochlorperazine, Compazine®, Mellaril®, Phenergan®, Thorazine®, Trilafon® or MAO inhibitors (Eldepryl®, Marplan®, Nardil®, or Parnate®).

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding.
  • Make sure your doctor knows if you have heart problems such as heart rhythm problems or high blood pressure or low blood pressure.
  • Tell your doctor if you have lung disease, liver disease, or nerve diseases.
  • This medicine will temporarily numb your skin or a part of your body. It could make it difficult for you to walk. Be careful not to injure the treated area. Avoid scratching or rubbing your skin and avoid extreme hot or cold temperature until the medicine stops working.
  • If you receive this medicine during childbirth, your baby may be sleepy or have muscle weakness for the first day or two after birth.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Change in how much or how often you urinate, or diarrhea.
  • Anxiety, dizziness, ringing in your ears, depression, or drowsiness.
  • Fainting or lightheadedness.
  • Fast, slow, or uneven heartbeat.
  • Fever or increased sweating.
  • Loss of movement of any part of your body or legs.
  • Tremors or seizures.

If you notice these less serious side effects, talk with your doctor:

  • Headache or pain in your back.
  • Increased sweating.
  • Problems having sex.
  • Temporary loss of sensation of any part of your body.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 10/4/2014


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