Medical Services Patients & Visitors Health Information For Medical Professionals Quality About Us
Text Size:  -   +  |  Print Page  |  Email Page

Dextroamphetamine (By mouth)

Dextroamphetamine (dex-troe-am-FET-a-meen)

Treats attention-deficit/hyperactivity disorder (ADHD). Also treats narcolepsy.

Brand Name(s):

Dexedrine, Dexedrine Spansule, Dexedrine Spansules, ProCentra, Zenzedi

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use it if you had an allergic reaction to dextroamphetamine or similar medicines, or if you have glaucoma or a history of drug abuse.

How to Use This Medicine:

Long Acting Capsule, Liquid, Tablet

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
  • Extended-release capsule for ADHD: It is best to take this medicine in the morning. This medicine could make it harder for you to sleep if you take it in the afternoon or evening.
  • Short-acting tablet: Take your last dose for the day at least 6 hours before bedtime, unless your doctor gives you other instructions.
  • Swallow the extended-release capsule whole. Do not crush, break, or chew it.
  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Do not use this medicine if you have used an MAO inhibitor (MAOI) within the past 14 days.
  • Some medicines can affect how dextroamphetamine works. Tell your doctor if you are also using any of the following:
    • Acetazolamide, chlorpromazine, ethosuximide, glutamic acid, guanethidine, haloperidol, hydrochlorothiazide, lithium, methenamine, phenobarbital, phenytoin, reserpine, or sodium acid phosphate
    • Sodium bicarbonate or other antacid
    • An antihistamine
    • Medicine to treat depression
    • Blood pressure medicine
    • Certain pain medicines (such as meperidine, propoxyphene)
  • Tell your doctor if you drink fruit juice.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding, or if you have heart disease (including heart rhythm problems), high blood pressure, blood vessel problems, thyroid problems, muscle or vocal tics or Tourette syndrome, or a history of heart attack, stroke, or seizures. Tell your doctor if you or anyone in your family has a history of depression, bipolar illness, suicide, mental health problems, or drug or alcohol problems.
  • This medicine may cause the following problems:
    • Raynaud phenomenon (blood circulation problem in your fingers or toes)
    • Unusual behavior or mood changes
    • Slow growth in children
  • This medicine can be habit-forming. Do not use more than your prescribed dose. Call your doctor if you think your medicine is not working.
  • This medicine may make you dizzy or cause blurred vision. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blurred vision or changes in vision
  • Chest pain that may spread to your arms, jaw, back, or neck, trouble breathing, nausea, unusual sweating, faintness
  • Extreme energy, confusion, anxiety, agitation, restlessness, unusual moods or behaviors
  • Fast, pounding, or uneven heartbeat
  • Numbness or weakness in your arm, leg, or on one side of your body
  • Seeing, hearing, or feeling things that are not there
  • Seizures
  • Unexplained sores, coldness, numbness, or color changes on your fingers or toes

If you notice these less serious side effects, talk with your doctor:

  • Dry mouth
  • Loss of appetite, weight loss
  • Trouble sleeping, tremors
  • Vomiting, diarrhea, or stomach pain

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 3/4/2015


The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites.
Copyright © 1984- Truven Health Analytics. All rights reserved.

Thomson & A.D.A.M
A.D.A.M. content is best viewed in IE9 or above, Fire Fox and chrome browser.