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Hydrocortisone/lidocaine (On the skin)

Hydrocortisone (hye-droe-KOR-ti-sone), Lidocaine (LYE-doe-kane)

Treats skin swelling, redness, itching, and discomfort caused by insect bites, mild burns, skin rashes, hemorrhoids, and other reasons.

Brand Name(s):

Lida Mantle HC, LidaZone HC

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to lidocaine or hydrocortisone. You might not be able to use this medicine if you have had an allergic reaction to an anesthetic in the past. You should not use this medicine if you have tuberculosis (TB), or to treat a fungal infection, chickenpox, or herpes.

How to Use This Medicine:

Cream, Lotion, Pad

  • Take your medicine as directed.
  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
  • This medicine is for use on your skin only. Do not get it in your eyes, nose, or mouth. If it does get on these areas, rinse it off right away.
  • Wash your hands with soap and water before and after you use this medicine.
  • Apply a thin layer of the medicine to the affected area. Rub it in gently.
  • Do not cover the treated area with a bandage unless directed by your doctor.

If a dose is missed:

  • Apply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine:

  • Store at room temperature away from heat and direct light. Do not freeze.
  • Ask your pharmacist or doctor how to dispose of the medicine container and any leftover or expired medicine.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.
  • Do not put cosmetics or skin care products on the treated skin.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breast feeding, or if you have diabetes or Cushing's syndrome. Tell your doctor if you have liver disease or kidney disease.
  • Do not use this medicine to treat a skin problem your doctor has not examined.
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • This medicine may raise or lower your blood sugar level.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Severe redness or swelling of treated area.

If you notice these less serious side effects, talk with your doctor:

  • Mild irritation of treated area.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 11/4/2014


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