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Buprenorphine (By mouth)

Buprenorphine (bue-pre-NOR-feen)

Treats addiction to narcotic pain relievers.

Brand Name(s):

Subutex

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to buprenorphine.

How to Use This Medicine:

Tablet

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

If a dose is missed:

  • You must use this medicine on a fixed schedule. Call your doctor or pharmacist if you miss a dose.

How to Store and Dispose of This Medicine:

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using a sedative such as Valium® or Xanax®. Tell your doctor if you are also using an antibiotic such as erythromycin (E-Mycin®, Ery-Tab®), or medicine to treat a fungal infection such as ketoconazole (Nizoral®). Tell your doctor if you use medicine to treat HIV or AIDS, such as ritonavir, indinavir, saquinavir, Crixivan®, Invirase®, or Norvir®.
  • Tell your doctor if you drink alcohol or if you are using any medicine that makes you sleepy, such as allergy medicine or narcotic pain medicine.
  • Do not drink alcohol while you are using this medicine.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant. You should not breast feed while you are using this medicine.
  • Make sure your doctor knows if you have liver disease, lung disease, kidney disease, an underactive thyroid, or an adrenal gland problem. Tell your doctor if you have problems with urination, an enlarged prostate, or mental illness.
  • Make sure your doctor knows if you have ever had a head injury, brain tumor, or stroke.
  • This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
  • Make sure any doctor or medical professional who treats you know that you are using this medicine.
  • This medicine can be habit-forming. Do not use more than your prescribed dose. Call your doctor if you think your medicine is not working.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Dark-colored urine or pale stools.
  • Fever, chills, cough, sore throat, and body aches.
  • Lightheadedness or fainting.
  • Nausea, vomiting, loss of appetite, pain in your upper stomach.
  • Shallow breathing.
  • Yellowing of your skin or the whites of your eyes.

If you notice these less serious side effects, talk with your doctor:

  • Headache, anxiety, or depression, or nervousness.
  • Increased sweating.
  • Mild stomach pain, nausea, vomiting, or constipation.
  • Pain, weakness or tired feeling, or trouble sleeping.
  • Runny or stuffy nose.
  • Warmth or redness in your face, neck, or chest.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 4/4/2014
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