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Buprenorphine (By mouth)

Buprenorphine (bue-pre-NOR-feen)

Treats addiction to narcotic pain relievers.

Brand Name(s):

Subutex

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use it if you had an allergic reaction to buprenorphine.

How to Use This Medicine:

Tablet

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
  • Missed dose: You must use this medicine on a fixed schedule. Call your doctor or pharmacist if you miss a dose.
  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines can affect how buprenorphine works. Tell your doctor if you are taking any of the following:
    • Erythromycin
    • HIV or AIDS medicine, such as ritonavir, indinavir, saquinavir
    • Ketoconazole
  • Tell your doctor if you drink alcohol or if you are using any medicine that makes you sleepy, such as allergy medicine or narcotic pain medicine.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding, or if you have liver, lung, or kidney disease, an underactive thyroid, an adrenal gland problem, problems with urination, an enlarged prostate, or mental illness. Tell your doctor if you have ever had a head injury, brain tumor, or stroke.
  • This medicine may cause a serious liver problem.
  • This medicine may make you dizzy or drowsy. Do not drive or do anything that could be dangerous until you know how this medicine affects you.
  • Tell any healthcare provider who treats you that you are using this medicine.
  • This medicine can be habit-forming. Do not use more than your prescribed dose. Call your doctor if you think your medicine is not working.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
  • Lightheadedness or fainting
  • Shallow breathing

If you notice these less serious side effects, talk with your doctor:

  • Anxiety, depression, or nervousness
  • Headache, pain, weakness or tired feeling, or trouble sleeping
  • Increased sweating
  • Warmth or redness in your face, neck, or chest

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 8/4/2014


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