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Alglucosidase alfa (Injection)

Alglucosidase Alfa (al-gloo-KOE-si-dase AL-fa)

Treats Pompe disease.

Brand Name(s):

Lumizyme, Myozyme

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not receive it if you had an allergic reaction to alglucosidase alfa.

How to Use This Medicine:

Injectable

  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
  • A nurse or other health provider will give you this medicine.
  • This medicine must be given slowly, so the needle will remain in place for a few hours. You may also receive medicines to help prevent possible allergic reactions to the injection.
  • Missed dose: Call your doctor or pharmacist for instructions.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding, or if you have heart or lung disease.
  • This medicine may cause a severe allergic reaction several hours after you receive it. Seek medical care right away if you have any signs of an allergic reaction, such as a rash, trouble breathing, or swelling in your face or throat.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blue lips, fingernails, or skin
  • Chest pain or trouble breathing
  • Ear pain or discharge, trouble hearing
  • Fast or slow heartbeat
  • Fever, chills, sore throat, and body aches
  • Shortness of breath and a cold sweat
  • Swelling in your face, around your eyes, or in your hands, ankles, or feet
  • Swollen, painful, or tender lymph glands in your neck, armpit, or groin

If you notice these less serious side effects, talk with your doctor:

  • Increased sweating or tearing
  • Nausea, vomiting, diarrhea, constipation, upset stomach, or stomach pain
  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
  • Pale skin
  • Warmth or redness in your face, neck, arms, or upper chest

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 8/4/2014


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