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Ibuprofen lysine (Injection)

Ibuprofen Lysine (eye-bue-PROE-fen LYE-seen)

Treats a heart condition known as patent ductus arteriosus (PDA) in premature babies.

Brand Name(s):

Neoprofen

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

Your child should not receive this medicine if your child has had an allergic reaction to ibuprofen lysine, or if your child has an untreated infection, kidney problems, bleeding problems, certain intestinal problems, or congenital heart disease such as pulmonary atresia, severe tetralogy of Fallot, or severe coarctation of the aorta.

How to Use This Medicine:

Injectable

  • A nurse or other trained health professional will give your child this medicine.
  • This medicine is given to your child through a needle placed in one of the veins.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your child's doctor knows about all the medicines your child is receiving.

Warnings While Using This Medicine:

  • Make sure your child's doctor knows if your child has any infection, liver disease, bleeding disorder, or bleeding in the brain, stomach, or intestines.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your child's face or hands, swelling or tingling in your child's mouth or throat, chest tightness, trouble breathing.
  • Absence of bowel movement or stools.
  • Bulge or lump on your child's groin.
  • Fast, slow, or uneven heartbeat.
  • High fever and chills.
  • Red or dark brown urine, or change in the number of wet diapers each day.
  • Seizures.
  • Severe vomiting or bloated belly.
  • Swelling in your child's hands, ankles, or feet.
  • Trouble breathing, or bluish-colored skin.
  • Unusual bleeding, bruising, or weakness.
  • Yellowing of the skin or the whites of your child's eyes.

If you notice these less serious side effects, talk with your doctor:

  • Diarrhea or vomiting.
  • Poor feeding.
  • Redness, swelling, rash, or a lump under your child's skin where the needle is placed.
  • Runny or stuffy nose.
  • Skin rash.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 9/4/2014


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