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Lanreotide (Subcutaneous)

Lanreotide (lan-REE-oh-tide)

Treats acromegaly (a growth hormone disorder) and tumors in the stomach, bowels, or pancreas.

Brand Name(s):

Somatuline Depot

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is generally considered safe for most people. Talk to your doctor if you have concerns.

How to Use This Medicine:


  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin.
  • A nurse or other health provider will give you this medicine.
  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
  • Missed dose: Call your doctor or pharmacist for instructions.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines can affect how lanreotide works. Tell your doctor if you are using any of the following:
    • Bromocriptine, cyclosporine, quinidine, terfenadine
    • Blood pressure or heart medicine, such as beta-blockers
    • Insulin or diabetes medicine

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, diabetes, gallbladder disease, heart problems, or thyroid problems.
  • This medicine may cause the following problems:
    • Gallstones
    • Changes in blood sugar level
    • High blood pressure
  • This medicine may make you dizzy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Increased thirst, hunger, or urination
  • Severe stomach pain with nausea and vomiting, yellow skin or eyes
  • Shaking, trembling, sweating, fast or pounding heartbeat, lightheadedness, confusion
  • Slow heartbeat, trouble breathing
  • Unusual bleeding, bruising, or weakness

If you notice these less serious side effects, talk with your doctor:

  • Constipation, diarrhea, gas, nausea, vomiting, or stomach pain
  • Headache or dizziness
  • Joint or muscle pain
  • Pain, itching, or a lump under your skin where the shot is given
  • Weight loss

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 10/4/2015

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