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Methoxy polyethylene Glycol-epoetin beta (Injection)

Methoxy Polyethylene Glycol-Epoetin Beta (meth-OX-ee pol-ee-ETH-i-leen GLYE-kol e-POE-e-tin BAY-ta)

Treats anemia that is caused by kidney failure.

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to methoxy polyethylene glycol-epoetin beta, or if you have uncontrolled high blood pressure.

How to Use This Medicine:

Injectable

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin, or into a vein.
  • A nurse or other health provider will give you this medicine.
  • You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.
  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
  • You will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas.
  • Always wipe the top of the medicine bottle with an alcohol pad before each use.
  • Do not shake the bottle, and do not use the medicine if the liquid appears cloudy or if you see solid pieces inside the bottle.
  • Stick the needle into the rubber stopper at the top of the bottle. With the needle still stuck in the bottle, turn the bottle upside down and hold it at eye level.
  • Pull the plunger until it lines up with the number of your dose on the side of the syringe.
  • Gently tap the syringe with your finger to make any air bubbles float to the top of the syringe, just under the needle. Push the plunger in just enough so that the air bubbles go up into the bottle, and pull enough medicine back down into the syringe to make the correct dose.
  • Use a new needle and syringe each time you inject your medicine.
  • Carefully follow your doctor's instructions about any special diet.

If a dose is missed:

  • Call your doctor or pharmacist for instructions.

How to Store and Dispose of This Medicine:

  • If you store this medicine at home, keep it in the refrigerator, away from direct light. Do not freeze.
  • You may store the bottles at room temperature for up to 7 days. You may also store the prefilled syringes at room temperature for up to 30 days.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine, containers, and other supplies. Throw away old medicine after the expiration date has passed.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have heart disease, cancer, high blood pressure, a blood disorder (such as hemolytic anemia, sickle cell anemia, or thalassemia), or a history of stroke, blood clots or seizures.
  • This medicine may increase your risk of having blood clots or serious heart and blood vessel problems, such as heart attack or stroke. Check with your doctor right away if you start having chest pain, trouble breathing, sudden or severe headache, or problems with vision, speech, or walking.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • You may also need to monitor your blood pressure at home. If you notice any changes to your recommended blood pressure, call your doctor right away.
  • This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor right away if you have a rash; itching; swelling of the face, tongue, and throat; trouble breathing; or chest pain after you get the injection.
  • Keep using this medicine for as long as your doctor tells you to. Do not stop using it without first checking with your doctor, even if you feel better.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Change in how much or how often you urinate, or painful urination.
  • Chest pain, shortness of breath, or coughing up blood.
  • Fast, slow, or irregular heartbeat.
  • Fever, chills, cough, stuffy or runny nose, sore throat, and body aches.
  • Lightheadedness, dizziness, or fainting.
  • Numbness or weakness in your arm or leg, or on one side of your body.
  • Pain or swelling in your lower leg (calf).
  • Redness, pain, swelling, or itching where the shot was given.
  • Seizures.
  • Sudden or severe headache, problems with vision, speech, or walking.
  • Swelling in your hands, ankles, or feet.

If you notice these less serious side effects, talk with your doctor:

  • Back pain or muscle aches.
  • Diarrhea, constipation, or vomiting.
  • Mild headache.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 8/4/2014


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