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Gadoversetamide (Injection)

Gadoversetamide (gad-oh-ver-SET-a-mide)

Used in magnetic resonance imaging (MRI) scans. Helps your doctor to see images of your brain, spine, liver, and other parts of your body. This medicine is a gadolinium-based contrast agent (GBCA).

Brand Name(s):

Optimark

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not receive this medicine if you have had an allergic reaction to gadoversetamide, gadolinium, versetamide, or other gadolinium-based contrast agents. You should not receive this medicine if you have severe kidney problems.

How to Use This Medicine:

Injectable

  • A doctor or other trained health professional will give you this medicine. This medicine is given through a needle placed in one of your veins just before you have an MRI scan.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, anemia or other blood problems, asthma, diabetes, high blood pressure, or a history of an allergic reaction to any contrast agent. Tell your doctor if you have an allergic respiratory disease, seizures, or heart disease.
  • Check with your doctor right away if you have burning or itching of the skin; red or dark patches on the skin; skin swelling, hardening, or tightening; joint stiffness; limited range of motion in the arms and legs; pain that is deep in the hip bone or ribs; or muscle weakness after you get the injection. These may be symptoms of a serious condition called nephrogenic systemic fibrosis (NSF).
  • This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Check with your doctor or nurse right away if you have cold, clammy skin; confusion; dizziness; lightheadedness; a skin rash; itching; sweating; swelling of the face, tongue, and throat; trouble with breathing; or chest pain after you receive the medicine.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Change in how much or how often you urinate, or blood in your urine.
  • Chest pain.
  • Cold feeling, confusion, restlessness, or increased salivation.
  • Fast, slow, pounding, or uneven heartbeat.
  • Lightheadedness, dizziness, or fainting.
  • Muscle stiffness or weakness, stiff joints or trouble moving, or deep bone pain.
  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet.
  • Severe rash or redness on your skin.
  • Shortness of breath or troubled breathing.
  • Skin rash, swelling, hardness, tightness, burning, itching, or red or dark patches.

If you notice these less serious side effects, talk with your doctor:

  • Back pain.
  • Bad taste in your mouth.
  • Dry mouth, nausea, vomiting, diarrhea, or stomach pain or upset.
  • Headache.
  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed.
  • Stuffy or runny nose.
  • Weakness or tiredness.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 8/4/2014


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