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Deferiprone (By mouth)

Deferiprone (de-FER-i-prone)

Treats iron toxicity (too much iron in the blood). This medicine is an iron chelator (binder).

Brand Name(s):

Ferriprox

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. You should not use it if you had an allergic reaction to deferiprone, or if you are pregnant.

How to Use This Medicine:

Tablet

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
  • Take the first dose of this medicine in the morning, the second dose at midday, and the third dose in the evening with meals, unless your doctor tells you otherwise.
  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines can affect how deferiprone works. Tell your doctor if you are using any of the following:
    • Diclofenac
    • Probenecid
    • Silymarin (milk thistle)
    • A diuretic (water pill)
  • Do not take anything that contains aluminum, iron, or zinc within 4 hours before or after you take deferiprone. This includes antacids, multivitamins, and supplements.

Warnings While Using This Medicine:

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
  • Tell your doctor if you are breastfeeding, or if you have heart failure, heart rhythm problems, heart hypertrophy, any type of infection, or low magnesium or potassium levels in your blood.
  • This medicine may cause the following problems:
    • Heart rhythm problems
    • Low white blood cell count (can increase your risk of infection)
  • This medicine may cause your urine to turn red or brownish. This is normal.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Fast, pounding, or uneven heartbeat
  • Fever, chills, cough, sore throat, and body aches
  • Lightheadedness, dizziness, or fainting
  • Seizures

If you notice these less serious side effects, talk with your doctor:

  • Muscle or joint pain
  • Nausea, vomiting, or stomach pain

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 9/4/2014


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