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Belladonna/opium (Rectal)

Belladonna (bel-a-DON-a), Opium (OH-pee-um)

Relieves moderate to severe pain caused by ureteral spasm. Belongs to the group of medicines called narcotic analgesics (pain medicines).

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to belladonna, opium, or other narcotic medicines (such as morphine). You should not use this medicine if you have asthma, glaucoma, severe liver disease, severe kidney disease, respiratory depression (very slow breathing), seizures or epilepsy, or if you are suffering from acute alcohol withdrawal. Do not give this medicine to children 12 years of age and younger.

How to Use This Medicine:

Suppository

  • Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
  • Never take rectal suppositories by mouth.
  • Wash your hands with soap and water before and after using this medicine. Remove the foil or wrapper from the suppository before inserting it.
  • Moisten your finger and the suppository with water.
  • Lie on your left side with your left leg straight or slightly bent, and your right knee bent upward. Gently push the pointed end of the suppository into the rectum about 1 inch.
  • Keep lying down for about 15 minutes to keep the suppository from coming out before it melts. Then, wash your hands again.

If a dose is missed:

  • If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine:

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not refrigerate.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of the used medicine applicator(s), containers, and any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
  • Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, enlarged prostate, mental illness (such as psychosis), an underactive thyroid, or a glaucoma that is starting to appear. Tell your doctor if you have a history of head injuries or have been addicted to drugs or alcohol.
  • This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions.
  • This medicine may cause constipation. This is more common if you use it for a long time. Ask your doctor if you should also use a laxative to prevent and treat constipation.
  • Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Decrease in how much or how often you urinate, painful urination.
  • Fast pulse.
  • Severe constipation.

If you notice these less serious side effects, talk with your doctor:

  • Blurred vision or changes in color vision.
  • Difficulty seeing at night.
  • Dizziness or drowsiness.
  • Dry mouth.
  • Increased sensitivity of the eyes to sunlight.
  • Mild constipation, nausea, or vomiting.
  • Rash or itching skin.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 6/12/2013


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