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Asparaginase erwinia chrysanthemi (Injection)

Asparaginase Erwinia Chrysanthemi (as-PAR-a-jin-ase er-WIN-ee-ah kri-SAN-them-ee)

Treats acute lymphoblastic leukemia (ALL).

Brand Name(s):

Erwinaze

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use it if you had an allergic reaction, bleeding problems, blood clots, or pancreas problems from asparaginase Erwinia chrysanthemi.

How to Use This Medicine:

Injectable

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles.
  • You will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.
  • This medicine is sometimes given together with other medicines. It is important that you receive each medicine at the proper time. Ask your doctor to help you create a schedule.
  • Missed dose: This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding, or you have liver disease, bleeding problems, blood clotting problems, or diabetes.
  • This medicine may cause the following problems:
    • Inflamed pancreas (pancreatitis)
    • Liver problems
    • Serious bleeding or blood clotting problems
    • Serious changes in blood sugar levels, possibly permanent
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest pain, shortness of breath, or coughing up blood
  • Increase in how much or how often you urinate
  • Increased hunger or thirst, pale skin, sweating
  • Numbness or weakness in your arm or leg, or on one side of your body
  • Pain or swelling in your calf
  • Sudden and severe stomach pain, chills, nausea, vomiting, fever, lightheadedness
  • Sudden or severe headache, confusion, or problems with vision, speech, or walking
  • Unusual bleeding

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 7/4/2014


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