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Canagliflozin (By mouth)

Canagliflozin (kan-a-gli-FLOE-zin)

Treats type 2 diabetes.

Brand Name(s):

Invokana

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use it if you had an allergic reaction to canagliflozin, or if you have severe kidney disease or are on dialysis.

How to Use This Medicine:

Tablet

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
  • It is best to take this medicine before the first meal of the day.
  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines and foods can affect how canagliflozin works. Tell your doctor if you are also using any of the following:
    • Blood pressure medicine, such as benazepril, enalapril, lisinopril
    • Digoxin
    • Diuretic (water pill)
    • Phenobarbital
    • Phenytoin
    • Rifampin
    • Ritonavir
  • Ask your doctor before you use any medicine, supplement, or salt substitute that contains potassium.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or high potassium or cholesterol levels.
  • This medicine may cause the following problems:
    • Low blood pressure
    • Vaginal yeast infections in women and yeast infections of the penis in men
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Extreme weakness, tiredness
  • Increased hunger, along with confusion, shaking, trembling, and sweating
  • Lightheadedness, dizziness, or fainting
  • Redness, itching, or swelling of the penis, pain in the skin around the penis, or bad-smelling discharge from the penis
  • Uneven heartbeat, trouble breathing, numbness or tingling in your hands, feet, or lips
  • Urinating less or less often than usual, difficult or painful urination
  • White or yellowish vaginal discharge, vaginal itching or odor

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 10/4/2014


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